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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDX2
All Species:
26.67
Human Site:
T212
Identified Species:
48.89
UniProt:
Q99626
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99626
NP_001256.2
313
33510
T212
F
H
Y
S
R
Y
I
T
I
R
R
K
A
E
L
Chimpanzee
Pan troglodytes
XP_522747
307
33029
T206
F
H
Y
S
R
Y
I
T
I
R
R
K
A
E
L
Rhesus Macaque
Macaca mulatta
XP_001096874
313
33566
T212
F
H
Y
S
R
Y
I
T
I
R
R
K
A
E
L
Dog
Lupus familis
XP_543154
314
33489
T212
F
H
Y
S
R
Y
I
T
I
R
R
K
A
E
L
Cat
Felis silvestris
Mouse
Mus musculus
P43241
311
33458
T211
F
H
F
S
R
Y
I
T
I
R
R
K
S
E
L
Rat
Rattus norvegicus
Q05095
123
14282
K59
W
F
Q
N
R
R
A
K
E
R
K
V
N
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519561
154
17330
K90
G
L
S
E
R
Q
V
K
I
W
F
Q
N
R
R
Chicken
Gallus gallus
Q9DEB6
260
28826
W196
T
E
R
Q
V
K
I
W
F
Q
N
R
R
A
K
Frog
Xenopus laevis
Q91622
263
29182
Q199
R
Q
V
K
I
W
F
Q
N
R
R
A
K
E
R
Zebra Danio
Brachydanio rerio
Q9YGT6
265
29507
Q201
R
T
A
Y
T
R
Y
Q
T
L
E
L
E
K
E
Tiger Blowfish
Takifugu rubipres
O13074
288
32704
K214
W
F
Q
N
R
R
M
K
W
K
K
D
H
K
L
Fruit Fly
Dros. melanogaster
P09085
427
45708
T299
Y
C
T
S
R
Y
I
T
I
R
R
K
S
E
L
Honey Bee
Apis mellifera
XP_001122398
358
40117
T251
F
H
Y
S
R
Y
I
T
I
R
R
K
A
E
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.8
98.4
96.1
N.A.
92.9
27.1
N.A.
36.7
50.4
47.2
23.9
26.8
27.6
31.5
N.A.
N.A.
Protein Similarity:
100
83.7
98.4
97.1
N.A.
94.5
28.7
N.A.
41.2
57.5
58.1
38.9
39.6
38.1
44.4
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
13.3
N.A.
13.3
6.6
20
0
13.3
73.3
100
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
26.6
20
26.6
6.6
53.3
86.6
100
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
0
0
0
0
8
39
8
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
8
0
8
0
0
0
0
8
0
8
0
8
62
8
% E
% Phe:
47
16
8
0
0
0
8
0
8
0
8
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
47
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
8
0
62
0
62
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
8
0
24
0
8
16
54
8
24
16
% K
% Leu:
0
8
0
0
0
0
0
0
0
8
0
8
0
0
62
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
16
0
0
0
0
8
0
8
0
16
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
16
8
0
8
0
16
0
8
0
8
0
0
0
% Q
% Arg:
16
0
8
0
77
24
0
0
0
70
62
8
8
8
16
% R
% Ser:
0
0
8
54
0
0
0
0
0
0
0
0
16
0
0
% S
% Thr:
8
8
8
0
8
0
0
54
8
0
0
0
0
0
0
% T
% Val:
0
0
8
0
8
0
8
0
0
0
0
8
0
0
0
% V
% Trp:
16
0
0
0
0
8
0
8
8
8
0
0
0
0
0
% W
% Tyr:
8
0
39
8
0
54
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _